Involvement of gangliosides in the interaction between BK virus and Vero cells

L Sinibaldi; P Goldoni; V Pietropaolo; C Longhi; N Orsi

doi:10.1007/BF01316682

Involvement of gangliosides in the interaction between BK virus and Vero cells

Arch Virol. 1990;113(3-4):291-6. doi: 10.1007/BF01316682.

Authors

L Sinibaldi¹, P Goldoni, V Pietropaolo, C Longhi, N Orsi

Affiliation

¹ Istituto di Microbiologia, Facoltà di Medicina e Chirurgia, Università di Roma La Sapienza, Italy.

PMID: 2171462
DOI: 10.1007/BF01316682

Abstract

BK virus infectivity was inhibited by gangliosides extracted from Vero cells and by standard preparations of different gangliosides. Gangliosides were also able to restore the susceptibility of glycosidase-treated Vero cells to BK virus infection.

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Animals
BK Virus / pathogenicity*
Gangliosides / physiology*
Neuraminidase
Vero Cells
beta-Galactosidase

Substances

Gangliosides
Neuraminidase
beta-Galactosidase