Steroids for patients in septic shock: the results of the CORTICUS trial

Alina Toma; Angela Stone; Robert S Green; Sara Gray

doi:10.2310/8000.2011.110243

Steroids for patients in septic shock: the results of the CORTICUS trial

CJEM. 2011 Jul;13(4):273-6. doi: 10.2310/8000.2011.110243.

Authors

Alina Toma¹, Angela Stone, Robert S Green, Sara Gray

Affiliation

¹ Department of Medicine, Division of Critical Care Medicine, University of Toronto, Toronto, ON, Canada.

PMID: 21722557
DOI: 10.2310/8000.2011.110243

Abstract

Clinical question: What is the role of steroids in septic shock in the emergency department?

Article chosen: Sprung CL, Annane D, Keh D, et al; CORTICUS Study Group. Hydrocortisone therapy for patients with septic shock. N Engl J Med 2008;358:111-24.

Study objective: To assess the safety and efficacy of low-dose hydrocortisone therapy for patients with septic shock and to compare outcomes based on response to corticotropin testing.

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