Central venous catheter-related blood stream infections in children undergoing hematopoietic stem cell transplant for primary immunodeficiency and other nonmalignant disorders

Pediatr Infect Dis J. 2011 Dec;30(12):1098-100. doi: 10.1097/INF.0b013e31822940a8.

Abstract

A single-center experience of catheter-related blood stream infections in children undergoing hematopoietic stem cell transplant for primary immunodeficiency is described. The rate of definite central venous catheter infections was 5.31/1000 line days. Staphylococcus epidermidis was the most commonly identified organism. Teicoplanin resistance occurred in 17% of S. epidermidis infections. The central catheter was removed in 21% of infections.

MeSH terms

  • Adolescent
  • Anti-Bacterial Agents / therapeutic use
  • Antifungal Agents / therapeutic use
  • Bacteremia / drug therapy
  • Bacteremia / etiology*
  • Bacteremia / microbiology
  • Catheter-Related Infections / drug therapy
  • Catheter-Related Infections / etiology*
  • Catheter-Related Infections / microbiology
  • Catheterization, Central Venous / adverse effects*
  • Child
  • Child, Preschool
  • Female
  • Gram-Negative Bacteria / isolation & purification
  • Hematopoietic Stem Cell Transplantation*
  • Humans
  • Immunologic Deficiency Syndromes / microbiology
  • Immunologic Deficiency Syndromes / surgery
  • Immunologic Deficiency Syndromes / therapy*
  • Infant
  • Male
  • Retrospective Studies
  • Staphylococcus epidermidis / isolation & purification

Substances

  • Anti-Bacterial Agents
  • Antifungal Agents