Immunologic changes during Pandemic (H1N1) 2009, China

Emerg Infect Dis. 2011 Jun;17(6):1053-5. doi: 10.3201/eid/1706.100643.

Abstract

We analyzed changes in immunologic values over time for 28 hospitalized patients with pandemic (H1N1) 2009. Levels of interleukin-6, interferon-y, and interleukin-10 increased 1 day after illness onset and then decreased to baseline levels. Levels of virus-specific antibody were undetectable 1 day after illness onset and peaked 36 days later.

MeSH terms

  • Adolescent
  • Adult
  • Antibodies, Viral / blood
  • China / epidemiology
  • Cytokines / blood
  • Cytokines / immunology
  • Humans
  • Influenza A Virus, H1N1 Subtype / immunology*
  • Influenza, Human / blood
  • Influenza, Human / epidemiology*
  • Influenza, Human / immunology*
  • Lymphocyte Count
  • Middle Aged
  • Pandemics*
  • Young Adult

Substances

  • Antibodies, Viral
  • Cytokines