Plasmid construction for genetic modification of dicotyledonous plants with a glycolate oxidizing pathway

Genet Mol Res. 2011 Jul 6;10(3):1356-63. doi: 10.4238/vol10-3gmr1262.

Abstract

There are many kinds of dicotyledonous C(3) plants, which often release CO(2) fixed by photosynthesis and consume energy in photorespiration. In Escherichia coli, glycolate can be metabolized by an oxidation pathway that has some of the same compounds as dicotyledonous photorespiration. With the bacterial glycolate metabolism pathway, photorespiration of dicotyledonous plants is genetically modified for less CO(2) release and more biomass. In this study, two plasmids involved in this modification were constructed for targeting two enzymes of the glycolate oxidizing pathway, glyoxylate carboligase and tartronic semialdehyde reductase, and glycolate dehydrogenase in Arabidopsis thaliana mitochondria in this pathway. All three enzymes are located in chloroplast by transit peptide derived from Pisum sativum small unit of Rubisco. So far, some crops have been transformed by the two plasmids. Through transformation of the two plasmids, photosynthesis of dicotyledonous plants may be promoted more easily and release less CO(2) into the atmosphere.

MeSH terms

  • Alcohol Oxidoreductases / genetics*
  • Alcohol Oxidoreductases / metabolism
  • Amino Acid Sequence
  • Arabidopsis / genetics*
  • Arabidopsis Proteins / genetics
  • Arabidopsis Proteins / metabolism
  • Carboxy-Lyases / genetics*
  • Chloroplasts / genetics
  • Escherichia coli / genetics
  • Glycolates / metabolism*
  • Photosynthesis / genetics
  • Pisum sativum / genetics
  • Plants, Genetically Modified
  • Plasmids / genetics
  • Ribulose-Bisphosphate Carboxylase / genetics

Substances

  • Arabidopsis Proteins
  • Glycolates
  • Alcohol Oxidoreductases
  • GDH protein, Arabidopsis
  • glycollate oxidase
  • Carboxy-Lyases
  • Ribulose-Bisphosphate Carboxylase
  • tartronate-semialdehyde synthase