Abstract
Kidney transplant recipients are at a high risk for H1N1 infection associated complications during the current pandemic. Prevention of infection by immunization, together with early recognition and prompt antiviral treatment are critical. Post-exposure prophylaxis of H1N1 with oseltamivir was safe, effective and well tolerated to prevent H1N1 influenza A virus infection in newly transplanted renal allograft recipient receiving triple immunosuppression without any interaction with tacrolimus level. Oseltamivir was effective for post-exposure prophylaxis of H1N1 in close contact.
MeSH terms
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Adult
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Antiviral Agents / therapeutic use*
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Drug Interactions
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Fatal Outcome
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Female
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Humans
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Immunosuppressive Agents / therapeutic use*
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Influenza A Virus, H1N1 Subtype / drug effects*
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Influenza A Virus, H1N1 Subtype / isolation & purification
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Influenza, Human / prevention & control*
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Influenza, Human / transmission
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Kidney Failure, Chronic / complications
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Kidney Failure, Chronic / surgery*
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Kidney Transplantation*
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Male
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Middle Aged
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Oseltamivir / therapeutic use*
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Postoperative Complications / drug therapy
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Pregnancy
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Reverse Transcriptase Polymerase Chain Reaction
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Transplantation, Homologous
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Treatment Outcome
Substances
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Antiviral Agents
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Immunosuppressive Agents
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Oseltamivir