Thoracic endovascular aortic repair with homemade stent grafts: early and mid-term outcomes

Surg Today. 2011 Aug;41(8):1054-61. doi: 10.1007/s00595-010-4489-4. Epub 2011 Jul 20.

Abstract

Purpose: We reviewed our experience with homemade stent grafts in the repair of a variety of thoracic aortic lesions. The objective of this study was to assess the early and mid-term outcomes of this therapy.

Methods: From 1999 to 2007, homemade stent grafts were inserted in 88 patients with an atherosclerotic aneurysm, dissection, pseudoaneurysm, trauma, or rupture in the thoracic aorta. The endoprostheses were stainless steel Z-stents covered by a polyester graft, and were custom-designed for each patient.

Results: Placement of stent grafts was technically successful in 81 of the 88 patients (92%). Within 30 days after treatment, 3 patients died, 3 had a cerebral infarction, and 3 had onset of paraplegia or paraparesis. Primary endoleaks were observed in 8 patients (9%). During the mean follow-up period of 32 ± 26 months, 7 patients had persistent endoleaks and 7 had stent-graft migration. The aneurysm-related mortality rate was 7%. The rate of freedom from open-surgery conversion at 32 months was 89.0%.

Conclusions: Our early experience with elective and emergency thoracic endovascular aortic repair using homemade stent grafts provided therapeutic benefits to high-risk patients. Endoleaks and stent-graft migrations were the factors most commonly responsible for secondary intervention in the mid-term period. Careful follow-up of patients treated with this approach is needed to avoid major complications in the long term.

MeSH terms

  • Adolescent
  • Adult
  • Aged
  • Aged, 80 and over
  • Aorta, Thoracic*
  • Aortic Diseases / etiology
  • Aortic Diseases / pathology
  • Aortic Diseases / surgery*
  • Blood Vessel Prosthesis Implantation*
  • Blood Vessel Prosthesis*
  • Endovascular Procedures*
  • Female
  • Humans
  • Male
  • Middle Aged
  • Polyethylene Terephthalates
  • Prosthesis Design
  • Retrospective Studies
  • Stents*
  • Time Factors
  • Treatment Outcome
  • Young Adult

Substances

  • Polyethylene Terephthalates