Streptococcus suis meningitis with bilateral sensorineural hearing loss

Korean J Lab Med. 2011 Jul;31(3):205-11. doi: 10.3343/kjlm.2011.31.3.205. Epub 2011 Jun 28.

Abstract

Streptococcus suis infection is an emerging zoonosis in Asia. The most common disease manifestation is meningitis, which is often associated with hearing loss and cochleovestibular signs. S. suis infection in humans mainly occurs among risk groups that have frequent exposure to pigs or raw pork. Here, we report a case of S. suis meningitis in a 67-yr-old pig carcass handler, who presented with dizziness and sensorineural hearing loss followed by headaches. Gram-positive diplococci were isolated from cerebrospinal fluid (CSF) and blood cultures and showed gray-white colonies with α-hemolysis. S. suis was identified from CSF and blood cultures by using a Vitek 2 system (bioMérieux, France), API 20 STREP (bioMérieux), and performing 16S rRNA and tuf gene sequencing. Even after receiving antibiotic treatment, patients with S. suis infection frequently show complications such as hearing impairment and vestibular dysfunction. To the best of our knowledge, this is the first case of S. suis meningitis in Korea. Prevention through public health surveillance is recommended, especially for individuals who have occupational exposures to swine and raw pork.

Keywords: Hearing loss; Korea; Meningitis; Streptococcus suis.

Publication types

  • Case Reports

MeSH terms

  • Aged
  • Animals
  • Bacterial Proteins / genetics
  • Blood / microbiology
  • Cerebrospinal Fluid / microbiology
  • Hearing Loss, Bilateral / complications
  • Hearing Loss, Bilateral / diagnosis*
  • Hearing Loss, Bilateral / microbiology
  • Humans
  • Male
  • Meningitis, Bacterial / complications
  • Meningitis, Bacterial / diagnosis*
  • Meningitis, Bacterial / microbiology
  • Phylogeny
  • RNA, Ribosomal, 16S / genetics
  • Sequence Analysis, DNA
  • Streptococcus suis / classification
  • Streptococcus suis / genetics
  • Streptococcus suis / isolation & purification*
  • Swine
  • Tomography, X-Ray Computed

Substances

  • Bacterial Proteins
  • RNA, Ribosomal, 16S