Live birth outcome with trophectoderm biopsy, blastocyst vitrification, and single-nucleotide polymorphism microarray-based comprehensive chromosome screening in infertile patients

William B Schoolcraft; Nathan R Treff; John M Stevens; Kathleen Ferry; Mandy Katz-Jaffe; Richard T Scott Jr

doi:10.1016/j.fertnstert.2011.06.049

Live birth outcome with trophectoderm biopsy, blastocyst vitrification, and single-nucleotide polymorphism microarray-based comprehensive chromosome screening in infertile patients

Fertil Steril. 2011 Sep;96(3):638-40. doi: 10.1016/j.fertnstert.2011.06.049. Epub 2011 Jul 23.

Authors

William B Schoolcraft¹, Nathan R Treff, John M Stevens, Kathleen Ferry, Mandy Katz-Jaffe, Richard T Scott Jr

Affiliation

¹ Colorado Center for Reproductive Medicine, Lone Tree, CO 80124, USA.

PMID: 21782169
DOI: 10.1016/j.fertnstert.2011.06.049

Abstract

The combination of trophectoderm biopsy, blastocyst vitrification, and single-nucleotide polymorphism microarray-based technology for comprehensive chromosome screening results in high implantation and live birth rates that could contribute to the practical application of single embryo transfer for infertility patients.

Publication types

Clinical Trial

MeSH terms

Abortion, Spontaneous / epidemiology
Adult
Biopsy / statistics & numerical data
Blastocyst / cytology*
Blastocyst / physiology
Chromosome Aberrations* / statistics & numerical data
Cryopreservation / methods
Cryopreservation / statistics & numerical data
Female
Humans
Infertility / epidemiology
Infertility / therapy*
Oligonucleotide Array Sequence Analysis
Polymorphism, Single Nucleotide
Pregnancy
Pregnancy Outcome / epidemiology
Pregnancy Rate*
Preimplantation Diagnosis / methods*
Preimplantation Diagnosis / statistics & numerical data
Single Embryo Transfer / methods*
Single Embryo Transfer / statistics & numerical data
Vitrification