Auditory N1 as a change-related automatic response

Neurosci Res. 2011 Oct;71(2):145-8. doi: 10.1016/j.neures.2011.07.004. Epub 2011 Jul 20.

Abstract

To test the hypothesis that the N1 component of auditory evoked potentials (AEPs) is one form of the change-related response elicited by an abrupt change in sound pressure from a silent background, two AEP experiments were conducted. Change-N1 was evoked by a test stimulus at 70dB following a 3-s conditioning stimulus of 0-69dB. On-N1 was evoked by the test sound alone at various sound pressures. As the physical difference between stimuli increased, the amplitude of Change-N1 increased, and the latency shortened. The amplitude and latency of On-N1 showed a similar pattern to the Change-N1 response. These results support the idea that On-N1 is a change-related component elicited by a sound pressure change.

Publication types

  • Comparative Study

MeSH terms

  • Acoustic Stimulation / methods*
  • Adult
  • Evoked Potentials, Auditory / physiology*
  • Female
  • Humans
  • Male
  • Middle Aged
  • Reaction Time / physiology*