An active site mutant of human placental alkaline phosphatase with deficient enzymatic activity and preserved immunoreactivity

Clin Chim Acta. 1990 Jan 15;186(2):189-96. doi: 10.1016/0009-8981(90)90036-r.
No abstract available

Publication types

  • Research Support, U.S. Gov't, P.H.S.

MeSH terms

  • Alkaline Phosphatase / biosynthesis*
  • Alkaline Phosphatase / genetics
  • Alkaline Phosphatase / immunology
  • Binding Sites
  • Cell Line
  • DNA / analysis
  • Escherichia coli / enzymology
  • Genetic Vectors
  • Humans
  • Mutation
  • Placenta / enzymology*
  • Plasmids / genetics*
  • Protein Conformation
  • Protein Engineering
  • Recombinant Proteins / biosynthesis
  • Structure-Activity Relationship
  • Transfection*

Substances

  • Recombinant Proteins
  • DNA
  • Alkaline Phosphatase