Abstract
Resistance to insulin action is a feature that accompanies certain diseases among which chronic inflammatory states like rheumatoid arthritis are included. What is, what its pathogenesis is, how it is measured, and what clinical and therapeutic implications have in rheumatoid arthritis patients is a topic not familiar to rheumatologists that is reviewed in this paper.
Copyright © 2010 Elsevier España, S.L. All rights reserved.
Publication types
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English Abstract
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Research Support, Non-U.S. Gov't
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Review
MeSH terms
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Adrenal Cortex Hormones / adverse effects
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Adrenal Cortex Hormones / therapeutic use
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Anti-Inflammatory Agents / therapeutic use
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Antirheumatic Agents / therapeutic use
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Arthritis, Rheumatoid / drug therapy
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Arthritis, Rheumatoid / metabolism*
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Biological Therapy
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Chronic Disease
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Cytokines / physiology
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Glucose Clamp Technique
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Glucose Tolerance Test
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Homeostasis
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Humans
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Inflammation / metabolism
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Insulin Resistance* / physiology
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Models, Biological
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NF-kappa B / antagonists & inhibitors
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Tumor Necrosis Factor-alpha / antagonists & inhibitors
Substances
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Adrenal Cortex Hormones
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Anti-Inflammatory Agents
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Antirheumatic Agents
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Cytokines
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NF-kappa B
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Tumor Necrosis Factor-alpha