Delayed endovascular revascularization in a patient with progressive neurological deterioration from bilateral intracranial vertebral artery occlusions: case report

Neurosurgery. 2011 Jul;69(1):E251-6; discussion E256. doi: 10.1227/NEU.0b013e3182186811.

Abstract

Background and importance: This article describes delayed endovascular revascularization in a patient with clinical and radiographic evidence of posterior circulation hemodynamic failure in the setting of intracranial occlusive lesions.

Clinical presentation: A 48-year-old man presented with a 6-week history of progressive headache, nausea, and ataxia. Bilateral intracranial vertebral artery occlusions and a left posterior inferior cerebellar artery stroke were diagnosed, and the patient began warfarin therapy. Despite these measures, the patient developed dense lower cranial neuropathies, including severe dysarthria, decreased left-sided hearing acuity, and left facial droop. He presented at this point for endovascular evaluation. The patient underwent successful revascularization with intravascular Wingspan stents (Boston Scientific, Natick, Massachusetts) in a delayed fashion (approximately 6 weeks after his initial stroke presentation). His neurological syndrome stabilized and began to improve slowly.

Conclusion: Patients with arterial occlusion should be evaluated acutely for potential revascularization. In the posterior circulation, clinical progression may supplant physiological imaging in the assessment of hemodynamic collapse. A subpopulation of patients will present with progressive deficits distinct from extracranial manifestations of vertebrobasilar insufficiency; these patients should be considered for delayed revascularization.

Publication types

  • Case Reports

MeSH terms

  • Arterial Occlusive Diseases / complications
  • Arterial Occlusive Diseases / diagnosis
  • Arterial Occlusive Diseases / surgery*
  • Cerebral Angiography / methods
  • Cerebral Revascularization / methods*
  • Disease Progression
  • Humans
  • Magnetic Resonance Imaging / methods
  • Male
  • Middle Aged
  • Vertebrobasilar Insufficiency / complications
  • Vertebrobasilar Insufficiency / diagnosis
  • Vertebrobasilar Insufficiency / surgery*