Platensimycin and its relatives: a recent story in the struggle to develop new naturally derived antibiotics

Nat Prod Rep. 2011 Sep;28(9):1534-79. doi: 10.1039/c1np00010a. Epub 2011 Aug 2.

Authors

Muhammad Saleem¹, Hidayat Hussain, Ishtiaq Ahmed, Teunis van Ree, Karsten Krohn

Affiliation

¹ Department of Chemistry, Baghdad-ul-Jadeed Campus, The Islamia University of Bahawalpur, 63100 Bahawalpur, Pakistan. [email protected]

PMID: 21808805
DOI: 10.1039/c1np00010a

No abstract available

Publication types

Review

MeSH terms

Adamantane / analogs & derivatives
Adamantane / chemical synthesis*
Adamantane / pharmacology
Aminobenzoates / chemical synthesis*
Aminobenzoates / pharmacology
Aminophenols / chemical synthesis*
Aminophenols / pharmacology
Anilides / chemical synthesis*
Anilides / pharmacology
Anti-Bacterial Agents / chemical synthesis*
Anti-Bacterial Agents / pharmacology
Biological Products / chemical synthesis*
Biological Products / pharmacology
Drug Design
Drug Resistance, Multiple / drug effects
Enterococcus faecalis / drug effects
Methicillin-Resistant Staphylococcus aureus / drug effects
Polycyclic Compounds / chemical synthesis*
Polycyclic Compounds / pharmacology
Streptococcus pneumoniae / drug effects
Structure-Activity Relationship

Substances

Aminobenzoates
Aminophenols
Anilides
Anti-Bacterial Agents
Biological Products
Polycyclic Compounds
carbaplatensimycin
Adamantane
platensimycin
platencin