Abstract
A series of mono and bis 2-2-(arylidineaminophenyl)indole azomethines have been synthesized by a condensation reaction of 2-(2-amino phenyl) indole with various mono and diketones R-CO-R(l) /R-CO-X-CO-R(l) (1:1/2:1 ratio) in ethanol media. The synthesized azomethines were characterized via IR, (1)H-NMR, (13)C-NMR, MS and elemental analysis. The antimicrobial activity of these compounds against different bacteria and fungi was also evaluated.
MeSH terms
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Anti-Infective Agents / analysis
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Anti-Infective Agents / chemical synthesis*
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Anti-Infective Agents / chemistry
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Anti-Infective Agents / pharmacology*
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Azo Compounds / analysis
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Azo Compounds / chemical synthesis*
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Azo Compounds / chemistry
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Azo Compounds / pharmacology*
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Bacteria / drug effects
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Fungi / drug effects
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Indoles / analysis
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Indoles / chemical synthesis
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Indoles / chemistry
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Indoles / pharmacology
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Microbial Sensitivity Tests
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Molecular Structure
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Structure-Activity Relationship
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Thiosemicarbazones / analysis
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Thiosemicarbazones / chemical synthesis*
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Thiosemicarbazones / chemistry
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Thiosemicarbazones / pharmacology*
Substances
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Anti-Infective Agents
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Azo Compounds
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Indoles
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Thiosemicarbazones
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azomethine