[Acute erythroblastopenia due to Parvovirus B19 revealing hereditary spherocytosis]

Arch Pediatr. 2011 Sep;18(9):990-2. doi: 10.1016/j.arcped.2011.06.009. Epub 2011 Aug 4.
[Article in French]

Abstract

Acute Parvovirus B19 infection is responsible for blocking the erythroblastic line, usually with no consequences on hematopoiesis except in patients with chronic hemolytic anemia in whom it can evolve to potentially serious acute anemia. We report 2 observations of acute erythroblastopenia revealing hereditary spherocytosis in 2 children (1 boy and 1 girl) of non-consanguineous parents.

Publication types

  • Case Reports
  • English Abstract

MeSH terms

  • Acute Disease
  • Adolescent
  • Blood Transfusion / methods
  • Child
  • Erythroblasts* / cytology
  • Female
  • Humans
  • Immunoglobulin M / blood
  • Immunologic Factors / blood
  • Male
  • Parvoviridae Infections / complications*
  • Parvovirus B19, Human* / isolation & purification
  • Pedigree
  • Red-Cell Aplasia, Pure / blood
  • Red-Cell Aplasia, Pure / therapy
  • Red-Cell Aplasia, Pure / virology*
  • Siblings*
  • Spherocytosis, Hereditary / complications*
  • Spherocytosis, Hereditary / diagnosis*
  • Treatment Outcome

Substances

  • Immunoglobulin M
  • Immunologic Factors