Abstract
Acute Parvovirus B19 infection is responsible for blocking the erythroblastic line, usually with no consequences on hematopoiesis except in patients with chronic hemolytic anemia in whom it can evolve to potentially serious acute anemia. We report 2 observations of acute erythroblastopenia revealing hereditary spherocytosis in 2 children (1 boy and 1 girl) of non-consanguineous parents.
Copyright © 2011. Published by Elsevier SAS.
Publication types
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Case Reports
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English Abstract
MeSH terms
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Acute Disease
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Adolescent
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Blood Transfusion / methods
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Child
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Erythroblasts* / cytology
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Female
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Humans
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Immunoglobulin M / blood
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Immunologic Factors / blood
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Male
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Parvoviridae Infections / complications*
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Parvovirus B19, Human* / isolation & purification
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Pedigree
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Red-Cell Aplasia, Pure / blood
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Red-Cell Aplasia, Pure / therapy
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Red-Cell Aplasia, Pure / virology*
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Siblings*
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Spherocytosis, Hereditary / complications*
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Spherocytosis, Hereditary / diagnosis*
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Treatment Outcome
Substances
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Immunoglobulin M
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Immunologic Factors