Abstract
A novel dimeric 1,4-benzoquinone and resorcinol derivative, Belamcandaquinone N (1), and two known compounds, 3-hydroxyirisquinone (2) and 5-[(Z)-10-heptadecenyl] resorcinol (3), were isolated from the seeds of Iris bungei Maxim. Their structures were elucidated by spectroscopic methods and comparing with literature data of known compounds. These compounds showed remarkable cytotoxic activity against RM-1 cell lines.
Copyright © 2011 Elsevier B.V. All rights reserved.
Publication types
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Research Support, Non-U.S. Gov't
MeSH terms
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Animals
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Antineoplastic Agents, Phytogenic / isolation & purification
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Antineoplastic Agents, Phytogenic / pharmacology
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Antineoplastic Agents, Phytogenic / therapeutic use*
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Benzoquinones / isolation & purification
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Benzoquinones / pharmacology
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Benzoquinones / therapeutic use*
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Cell Line, Tumor
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Iris Plant / chemistry*
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Male
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Mice
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Molecular Structure
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Phytotherapy*
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Plant Extracts / chemistry
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Plant Extracts / pharmacology
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Plant Extracts / therapeutic use
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Prostatic Neoplasms / drug therapy*
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Resorcinols / isolation & purification
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Resorcinols / pharmacology
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Resorcinols / therapeutic use*
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Seeds
Substances
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Antineoplastic Agents, Phytogenic
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Benzoquinones
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Plant Extracts
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Resorcinols
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belamcandaquinone N
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irisquinone