A case series and review of sporotrichosis in Sikkim

J Infect Dev Ctries. 2011 Aug 12;5(8):603-8. doi: 10.3855/jidc.1305.

Abstract

Sporotrichosis caused by the fungus Sporothrix schenckii has been widely reported from the northern Himalayan belt and the north eastern region of India. Three autochthonous cases of lymphocutaneous sporotrichosis from east and south districts of Sikkim are reported. Fluid aspirate from the nodulo-ulcerative lesions were sent for cytology and fungal culture. S. schenckii was isolated on culture and cytological examination in all three cases showed granulomatous reaction. Thermal dimorphism was demonstrated and animal pathogenicity testing was performed. Saturated solution of potassium iodide was used for treatment and the last case was treated with itraconazole and potassium iodide. Awareness of this disease and an extensive environmental study is required to understand the actual burden of this disease.

Publication types

  • Case Reports

MeSH terms

  • Adult
  • Animals
  • Antifungal Agents / therapeutic use
  • Dermatomycoses / drug therapy
  • Dermatomycoses / epidemiology*
  • Dermatomycoses / microbiology
  • Female
  • Humans
  • Itraconazole / therapeutic use
  • Lymphatic Diseases / drug therapy
  • Lymphatic Diseases / epidemiology*
  • Lymphatic Diseases / microbiology
  • Male
  • Mice
  • Middle Aged
  • Potassium Iodide / therapeutic use
  • Sikkim / epidemiology
  • Sporothrix / isolation & purification*
  • Sporothrix / pathogenicity
  • Sporotrichosis / drug therapy
  • Sporotrichosis / epidemiology*
  • Sporotrichosis / microbiology

Substances

  • Antifungal Agents
  • Potassium Iodide
  • Itraconazole