Early pregnancy complicated with juvenile granulosa cell tumor

Am J Med Sci. 2011 Nov;342(5):435-7. doi: 10.1097/MAJ.0b013e318229992c.

Abstract

Introduction: Granulosa cell tumors (GCTs) are extremely rare tumors and are divided into 2 types: adult (AGCT) and juvenile (JGCT). The JGCTs represent only 5% of all cases. The incidence of ovarian carcinoma diagnosed during pregnancy varies about 0.0179 to 0.11 per 1000 pregnancies.

Case: A 24-year-old woman at 12 weeks and 3 days of pregnancy was admitted to the authors' hospital due to a pelvic mass. Surgical exploration revealed a smooth, solid, mobile and well-encapsulated left ovarian mass. Histological and immunohistochemical findings led to the diagnosis of a well-differentiated JGCT. Pregnancy continued uncomplicated and she delivered a healthy baby girl at 37 weeks gestation. About 9 months after the original diagnosis, the patient showed no evidence of disease.

Conclusion: Treatment options and a review of the literature related to JGCTs are discussed.

Publication types

  • Case Reports

MeSH terms

  • Adult
  • Female
  • Granulosa Cell Tumor / pathology*
  • Granulosa Cell Tumor / surgery
  • Humans
  • Ovarian Neoplasms / pathology*
  • Ovarian Neoplasms / surgery
  • Pregnancy
  • Pregnancy Complications, Neoplastic / pathology*
  • Pregnancy Complications, Neoplastic / surgery
  • Treatment Outcome