A diffusion model decomposition of the effects of alcohol on perceptual decision making

Psychopharmacology (Berl). 2012 Feb;219(4):1017-25. doi: 10.1007/s00213-011-2435-9. Epub 2011 Aug 13.

Abstract

Rationale: Even in elementary cognitive tasks, alcohol consumption results in both cognitive and motor impairments (e.g., Schweizer and Vogel-Sprott, Exp Clin Psychopharmacol 16: 240-250, 2008).

Objectives: The purpose of this study is to quantify the latent psychological processes that underlie the alcohol-induced decrement in observed performance.

Methods: In a double-blind experiment, we administered three different amounts of alcohol to participants on different days: a placebo dose (0 g/l), a moderate dose (0.5 g/l), and a high dose (1 g/l). Following this, participants performed a "moving dots" perceptual discrimination task. We analyzed the data using the drift diffusion model. Model parameters drift rate, boundary separation, and non-decision time allow a decomposition of the alcohol effect in terms of their respective cognitive components, that is, rate of information processing, response caution, and non-decision processes (e.g., stimulus encoding, motor processes).

Results: We found that alcohol intoxication causes higher mean RTs and lower response accuracies. The diffusion model decomposition showed that alcohol intoxication caused a decrease in drift rate and an increase in non-decision time.

Conclusions: In a simple perceptual discrimination task, even a moderate dose of alcohol decreased the rate of information processing and negatively affected the non-decision component. However, alcohol consumption left response caution largely intact.

Publication types

  • Controlled Clinical Trial
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adolescent
  • Adult
  • Alcohol Drinking / adverse effects*
  • Alcoholic Intoxication / physiopathology
  • Cognition / drug effects
  • Decision Making / drug effects*
  • Discrimination Learning / drug effects
  • Dose-Response Relationship, Drug
  • Double-Blind Method
  • Ethanol / administration & dosage
  • Ethanol / adverse effects*
  • Humans
  • Male
  • Models, Psychological*
  • Pilot Projects
  • Reaction Time / drug effects
  • Time Factors
  • Young Adult

Substances

  • Ethanol