Candida albicans-induced chronic thrombocytopenic purpura

Acta Haematol. 2011;126(4):202-4. doi: 10.1159/000329901. Epub 2011 Aug 23.

Abstract

We present 2 patients with chronic immune thrombocytopenic purpura (ITP) secondary to Candida albicans infection. Neither patient responded to standard ITP therapy including splenectomy. Appropriate antifungal treatment of the C. albicans infection was followed by sustained improvement in platelet count in both patients. To our knowledge, this is the first report of ITP in association with C. albicans infection.

Publication types

  • Case Reports

MeSH terms

  • Adult
  • Antifungal Agents / therapeutic use
  • Candida albicans / immunology*
  • Candida albicans / isolation & purification
  • Candidiasis / drug therapy
  • Candidiasis / microbiology
  • Candidiasis / physiopathology*
  • Female
  • Humans
  • Purpura, Thrombocytopenic / etiology*
  • Purpura, Thrombocytopenic / immunology
  • Treatment Outcome
  • Vulvovaginitis / drug therapy
  • Vulvovaginitis / microbiology
  • Vulvovaginitis / physiopathology

Substances

  • Antifungal Agents