Clinical, tomographic, and angiographic findings in patients with acute toxoplasmic retinochoroiditis and associated serous retinal detachment

Ocul Immunol Inflamm. 2011 Oct;19(5):307-10. doi: 10.3109/09273948.2011.602501. Epub 2011 Aug 24.

Abstract

Purpose: To describe the clinical, optical coherence tomographic, and angiographic findings in patients with acute toxoplasmic retinochoroiditis (RC) associated with serous retinal detachment (SRD).

Methods: The study included 60 eyes with acute toxoplasmic RC.

Results: Of 60 eyes, 14 (23.3%) were found to have SRD. The SRD was visible on fundus examination in 6 cases and detectable only by optical coherence tomography (OCT) in the 8 remaining cases. It involved the fovea in 9 eyes. There was evidence of associated choroidal ischemia on fluorescein angiography and indocyanine green angiography in 5 eyes. Findings seen at the acute stage gradually resolved over a period of 2-6 weeks in all patients.

Conclusions: SRD, accurately detected by OCT, is a common complication of acute toxoplasmic RC that should be considered as a potential cause of visual loss. Choroidal ischemia might contribute to the development of such complication.

MeSH terms

  • Acute Disease
  • Adult
  • Antiprotozoal Agents / therapeutic use
  • Azithromycin / therapeutic use
  • Chorioretinitis / diagnosis*
  • Chorioretinitis / drug therapy
  • Chorioretinitis / parasitology
  • Female
  • Fluorescein Angiography
  • Humans
  • Indocyanine Green
  • Male
  • Prednisone / therapeutic use
  • Pyrimethamine / therapeutic use
  • Retinal Detachment / diagnosis*
  • Retinal Detachment / parasitology
  • Retinal Detachment / pathology
  • Tomography, Optical Coherence
  • Toxoplasmosis, Ocular / diagnosis*
  • Toxoplasmosis, Ocular / drug therapy
  • Toxoplasmosis, Ocular / pathology
  • Treatment Outcome
  • Young Adult

Substances

  • Antiprotozoal Agents
  • Azithromycin
  • Indocyanine Green
  • Prednisone
  • Pyrimethamine