Abstract
Deficits in inflammasomes, a key element of innate immunity, confer increased susceptibility to infection. We report that sputum cells from asthmatics have decreased expression of inflammasome factors, consistent with reports of increased infection risk in asthmatics.
Publication types
-
Letter
-
Research Support, N.I.H., Extramural
MeSH terms
-
Asthma / immunology
-
Asthma / metabolism*
-
Female
-
Gene Expression Regulation*
-
Humans
-
Inflammasomes / biosynthesis*
-
Inflammasomes / immunology
-
Male
-
Rhinitis / immunology
-
Rhinitis / metabolism*
-
Sputum / immunology
-
Sputum / metabolism*