Assessment of red cell distribution width (RDW) in patients with coronary artery ectasia

Clin Appl Thromb Hemost. 2012 Mar-Apr;18(2):211-4. doi: 10.1177/1076029611418964. Epub 2011 Aug 25.

Abstract

Objectives: Coronary artery ectasia (CAE) is characterized by an abnormal dilatation of the coronary arteries. Red cell distribution width (RDW) is a measure of heterogeneity in the size of red blood cell. In this study, we aimed to investigate RDW levels in patients with CAE.

Methods: The study population included 54 patients with CAE (28 males; mean age, 59 ± 12) and 40 individuals comprising the control group who had normal coronary arteries (17 males; mean age, 56 ± 10). Admission RDW was measured as part of the automated complete blood count.

Results: The RDW was significantly higher in the CAE group than the control (P < .001). Also, high-sensitive C-reactive protein (hs-CRP) levels in patients with CAE were significantly higher as compared with controls (P < .001).

Conclusion: This study demonstrates that RDW and hs-CRP were higher in the CAE group compared with the control group. These results show that RDW is a reliable, simple, and inexpensive marker for patients with CAE.

Publication types

  • Controlled Clinical Trial

MeSH terms

  • Aged
  • Biomarkers
  • Blood Cell Count
  • Blood Glucose / analysis
  • C-Reactive Protein / analysis
  • Coronary Angiography
  • Coronary Disease / blood*
  • Cross-Sectional Studies
  • Dilatation, Pathologic / blood
  • Erythrocyte Indices*
  • Female
  • Hemodynamics
  • Humans
  • Lipids / blood
  • Male
  • Middle Aged
  • Predictive Value of Tests
  • Prospective Studies
  • Risk Factors

Substances

  • Biomarkers
  • Blood Glucose
  • Lipids
  • C-Reactive Protein