The impact of recurrent laryngeal neuromonitoring on multi-dimensional voice outcomes following thyroid surgery

J Surg Oncol. 2012 Jan;105(1):4-9. doi: 10.1002/jso.22063. Epub 2011 Aug 22.

Abstract

Background: Voice changes after thyroidectomy are common but not always related to recurrent laryngeal nerve (RLN) injury. We evaluated if RLN neuromonitoring correlated with non-RLN injury-related changes in voice after thyroidectomy.

Methods: Prospective multi-dimensional voice assessment was conducted on patients undergoing thyroidectomy before, 1-4 weeks, and 6 months postoperatively. Voice outcome (VO) was determined as normal (NormVO) or negative (NegVO) based upon combinations of patient-reported symptoms, videolaryngoscopy, a composite of acoustic measurements, and clinician-perceived voice quality. Groups with and without neuromonitoring were compared for early and durable differences in VO.

Results: Ninety-one patients underwent thyroidectomy; 39 with RLN neuromonitoring and 52 without. The two study groups were similar with regard to baseline characteristics including voice assessment. There was no difference in NegVO between neuromonitored and non-monitored patients at 1-4 weeks (n = 89; 32% vs. 27%; P = 0.81) and 6 months (n = 71, 14% vs. 7%; P = 0.42) after thyroidectomy. Neuromonitoring was associated with a 48-min increase in median operative time, but this finding was not statistically significant in a multivariate model.

Conclusion: In this study, recurrent laryngeal neuromonitoring did not appear to influence non-RLN injury related VO as measured by a comprehensive multidimensional voice assessment.

Publication types

  • Research Support, U.S. Gov't, Non-P.H.S.

MeSH terms

  • Female
  • Follow-Up Studies
  • Humans
  • Male
  • Middle Aged
  • Postoperative Complications*
  • Prognosis
  • Prospective Studies
  • Recurrent Laryngeal Nerve / physiopathology*
  • Recurrent Laryngeal Nerve Injuries / diagnosis*
  • Recurrent Laryngeal Nerve Injuries / etiology
  • Thyroid Neoplasms / pathology
  • Thyroid Neoplasms / surgery*
  • Thyroidectomy / adverse effects*
  • Vocal Cords / physiopathology*
  • Voice Disorders / diagnosis*
  • Voice Disorders / etiology
  • Voice Quality