[Thyrotoxic hypokaliemic periodic paralysis revealing Graves' disease in a male Caucasian]

L Guilloton; A De Carvalho; L Quesnel; F Pasquet; C Mounier; A Drouet

doi:10.1016/j.neurol.2011.03.012

[Thyrotoxic hypokaliemic periodic paralysis revealing Graves' disease in a male Caucasian]

Rev Neurol (Paris). 2012 Feb;168(2):170-2. doi: 10.1016/j.neurol.2011.03.012. Epub 2011 Sep 1.

[Article in French]

Authors

L Guilloton¹, A De Carvalho, L Quesnel, F Pasquet, C Mounier, A Drouet

Affiliation

¹ Service de neurologie HIA Desgenettes, 108, boulevard Pinel, 69275 Lyon cedex 03, France. [email protected]

PMID: 21889178
DOI: 10.1016/j.neurol.2011.03.012

Abstract

Objectives: Hypokaliemic thyrotoxic periodic paralysis (TPP) is an uncommon complication of hyperthyroidism. Mostly described among Asian patients, it is rare in other ethnic groups, in particular in Caucasian people.

Case report: We present the case of a Caucasian male admitted to our unit after several paretic episodes. Tachycardia, goiter and mild proptosis led to the diagnosis of Graves' disease.

Conclusion: Rare in the Caucasian population, TPP involves dysfunction of the NA-K-ATPase pump. Beta-blockers should be associated with medical or surgical treatment of hyperthyroidism.

Publication types

Case Reports

MeSH terms

Adult
Diagnosis, Differential
Graves Disease / complications*
Graves Disease / diagnosis*
Graves Disease / ethnology
Humans
Hypokalemic Periodic Paralysis / diagnosis*
Hypokalemic Periodic Paralysis / etiology*
Male
Thyrotoxicosis / complications*
Thyrotoxicosis / diagnosis
White People