Emergence of carbapenemases in Gram-negative bacteria in Hamburg, Germany

Diagn Microbiol Infect Dis. 2011 Nov;71(3):312-5. doi: 10.1016/j.diagmicrobio.2011.07.011. Epub 2011 Sep 6.

Abstract

We analyzed a collection of carbapenem-resistant Gram-negative bacterial isolates and detected VIM-1, VIM-2, and KPC-2 in diverse enterobacterial species and Pseudomonas aeruginosa isolates. Our findings suggest a more widespread dissemination of carbapenemases in Germany than currently appreciated.

MeSH terms

  • Anti-Bacterial Agents / pharmacology*
  • Bacterial Proteins / genetics*
  • Carbapenems / pharmacology*
  • Drug Resistance, Multiple, Bacterial / genetics
  • Germany
  • Gram-Negative Bacteria / drug effects*
  • Gram-Negative Bacteria / genetics
  • Gram-Negative Bacteria / isolation & purification
  • Humans
  • Microbial Sensitivity Tests
  • beta-Lactamases / genetics*

Substances

  • Anti-Bacterial Agents
  • Bacterial Proteins
  • Carbapenems
  • beta-Lactamases
  • carbapenemase