Grass pollen allergens: detection on pollen grain surface using membrane print technique

Int Arch Allergy Appl Immunol. 1990;91(3):266-9. doi: 10.1159/000235126.

Abstract

A microtechnique is described to visualize pollen allergens by making prints from the surface of mature grains on nitrocellulose membrane. The allergen Lol p I is detected by specific monoclonal antibodies or specific IgE from sera of grass-pollen-allergic patients, visualized by the immunoperoxidase method. This technique offers the potential to study the distribution of individual allergens in aerobiology samples by bright-field microscopy, and to determine the sensitivity spectra of allergic individuals to known and unknown pollen sources.

MeSH terms

  • Allergens*
  • Antibodies, Monoclonal / immunology
  • Antigens, Plant
  • Immunoenzyme Techniques
  • Immunoglobulin E
  • Immunologic Techniques
  • Plant Proteins*
  • Poaceae / analysis*
  • Pollen / analysis*

Substances

  • Allergens
  • Antibodies, Monoclonal
  • Antigens, Plant
  • Lol p I protein, Lolium perenne
  • Plant Proteins
  • Immunoglobulin E