Discovery and development of α7 nicotinic acetylcholine receptor modulators

J Med Chem. 2011 Dec 8;54(23):7943-61. doi: 10.1021/jm2007672. Epub 2011 Sep 29.

Authors

Anatoly A Mazurov¹, Jason D Speake, Daniel Yohannes

Affiliation

¹ Targacept, Inc, Winston-Salem, North Carolina 27101-4165, United States. [email protected]

PMID: 21919481
DOI: 10.1021/jm2007672

No abstract available

Publication types

Review

MeSH terms

Allosteric Regulation
Animals
Clinical Trials as Topic
Drug Discovery
Humans
Nicotinic Agonists / chemistry*
Nicotinic Agonists / pharmacology
Nicotinic Agonists / therapeutic use
Nicotinic Antagonists / chemistry*
Nicotinic Antagonists / pharmacology
Receptors, Nicotinic / physiology*
Stereoisomerism
alpha7 Nicotinic Acetylcholine Receptor

Substances

Chrna7 protein, human
Nicotinic Agonists
Nicotinic Antagonists
Receptors, Nicotinic
alpha7 Nicotinic Acetylcholine Receptor