Recovery of advanced atrioventricular block by cilostazol

Intern Med. 2011;50(18):1957-61. doi: 10.2169/internalmedicine.50.5228. Epub 2011 Sep 15.

Abstract

We describe a case of advanced atrioventricular (AV) block, in which treatment with cilostazol was effective in recovering the AV conduction. The patient was referred to our hospital for close examination of the advanced AV block and permanent pacemaker implantation. Although the patient had experienced third-degree AV block with occasional AV synchrony for more than two days, the AV conduction completely recovered after treatment with oral cilostazol at 200 mg/day. Here we discuss the possible mechanism of the improvement in the AV conduction by cilostazol.

Publication types

  • Case Reports

MeSH terms

  • Aged, 80 and over
  • Atrioventricular Block / drug therapy*
  • Atrioventricular Block / physiopathology
  • Cilostazol
  • Electrocardiography
  • Female
  • Heart Conduction System / drug effects
  • Heart Conduction System / physiopathology
  • Humans
  • Phosphodiesterase 3 Inhibitors / pharmacology
  • Phosphodiesterase 3 Inhibitors / therapeutic use*
  • Tetrazoles / pharmacology
  • Tetrazoles / therapeutic use*
  • Treatment Outcome

Substances

  • Phosphodiesterase 3 Inhibitors
  • Tetrazoles
  • Cilostazol