18F-FDG PET/CT in primary AL hepatic amyloidosis associated with multiple myeloma

Korean J Radiol. 2011 Sep-Oct;12(5):634-7. doi: 10.3348/kjr.2011.12.5.634. Epub 2011 Aug 24.

Abstract

We report here on a rare case of primary AL hepatic amyloidosis associated with multiple myeloma in a 64-year-old woman. The patient was referred for evaluating her progressive jaundice and right upper quadrant pain. (18)F-fluorodeoxyglucose ((18)F-FDG) positron emission tomography (PET)/computed tomography (CT) showed diffusely and markedly increased (18)F-FDG uptake in the liver. Although there have been several case studies showing positive (18)F-FDG uptake in pulmonary amyloidosis, to the best of our knowledge, the (18)F-FDG PET/CT findings of hepatic amyloidosis or primary hepatic amyloidosis associated with multiple myeloma have not been reported previously.

Keywords: 18F-FDG PET; Amyloidosis; Liver; Multiple Myeloma.

Publication types

  • Case Reports

MeSH terms

  • Amyloidosis / complications
  • Amyloidosis / diagnostic imaging*
  • Amyloidosis / pathology
  • Biopsy, Needle
  • Female
  • Fluorodeoxyglucose F18*
  • Humans
  • Liver / pathology
  • Liver Diseases / complications
  • Liver Diseases / diagnostic imaging*
  • Liver Diseases / pathology
  • Middle Aged
  • Multimodal Imaging*
  • Multiple Myeloma / complications*
  • Positron-Emission Tomography*
  • Radiopharmaceuticals*
  • Tomography, X-Ray Computed*

Substances

  • Radiopharmaceuticals
  • Fluorodeoxyglucose F18