Neurotoxicity caused by intraarterial injection of low-dose low osmolar, iodinated contrast agents during radiologic studies is an extremely rare adverse event. Contrast medium induced disruption of the blood-brain barrier and a direct neurotoxic effect by contrast media have been proposed as a potential mechanism of neurotoxicity. This report describes an unusual case of transient neurotoxicity following diagnostic angiography mimicking clinically and radiologically subarachnoid hemorrhage. The patient recovered without any intervention after 4 days of conservative treatment.