Acute pericardial effusion following atrial fibrillation ablation: characteristics and relationship with arrhythmia recurrences

Arch Cardiovasc Dis. 2011 Aug;104(8-9):450-7. doi: 10.1016/j.acvd.2011.05.005. Epub 2011 Aug 27.

Abstract

Background: Pericardial effusion (PE) can occur during or after atrial fibrillation (AF) ablation, and may induce atrial arrhythmia.

Aim: To characterize the impact of PE on arrhythmia recurrences following AF ablation.

Methods: Patients referred for a first radiofrequency AF ablation were studied prospectively. Transthoracic echocardiography was performed before and 24h after the procedure. If PE was present, transthoracic echocardiography was repeated at 1 month to evaluate PE evolution. Early arrhythmia recurrences (EARs) were defined as any arrhythmia documented within 1 month of the procedure.

Results: PE was diagnosed in 18/81 patients (22%); and was present in significantly more patients with persistent versus paroxysmal AF (14/40 [35%] vs 4/41 [10%]; P=0.008). PEs were mild (mean 6 ± 3mm), mainly asymptomatic (89%), and none required pericardiocentesis. Early and late arrhythmia recurrences were present in 25/81 (31%) and 29/81 (36%), respectively. The incidence of PE was significantly higher among patients with EARs versus those without (12/25 [48%] vs 6/56 [11%]; P=0.0004). By multivariable analysis, PE and duration in AF were the two independent predictors of EARs. PE incidence was similar in patients with and without late arrhythmia recurrences. At 1 month, no patients had PE on transthoracic echocardiography.

Conclusion: PE following radiofrequency AF ablation is frequent, particularly following persistent AF ablation. This effusion is generally mild, mainly asymptomatic, and independently associated with EARs.

MeSH terms

  • Acute Disease
  • Adult
  • Aged
  • Atrial Fibrillation / diagnosis
  • Atrial Fibrillation / surgery*
  • Catheter Ablation / adverse effects*
  • Chi-Square Distribution
  • Echocardiography
  • Electrocardiography
  • Female
  • France
  • Humans
  • Logistic Models
  • Male
  • Middle Aged
  • Pericardial Effusion / diagnosis
  • Pericardial Effusion / etiology*
  • Prospective Studies
  • Recurrence
  • Risk Assessment
  • Risk Factors
  • Time Factors
  • Treatment Outcome