Mortality and morbidity of diabetic pregnancy have decreased markedly during the last decades. Abortions occur more frequently than in control women. Perinatal mortality has declined, especially in large centers. Morbidity remains important: two thirds of the infants experience some morbidity, mainly due to prematurity and malformations. Among factors of prognosis, careful control of maternal diabetes before conception until delivery is the main point. For each period of pregnancy, a bad glycemic control in the mother is associated with a complication in the infant. Hypertension and diabetic neuropathy are risk factors of prematurity. Congenital malformations become in the large centers the main source of mortality and morbidity in infants of diabetic mothers.