Active Toll-like receptor-7 triggering of chronic lymphocytic leukemia B-cells by imiquimod

Leuk Lymphoma. 2012 Apr;53(4):739-42. doi: 10.3109/10428194.2011.624230.
No abstract available

Publication types

  • Letter

MeSH terms

  • Aged
  • Aged, 80 and over
  • Aminoquinolines / pharmacology*
  • Antigens, CD19 / metabolism
  • Antineoplastic Agents / pharmacology
  • Apoptosis / drug effects*
  • CD5 Antigens / metabolism
  • Cytokines / metabolism*
  • Dose-Response Relationship, Drug
  • Female
  • Flow Cytometry
  • Humans
  • Imiquimod
  • In Situ Nick-End Labeling
  • Interleukin-6 / metabolism
  • Interleukin-8 / metabolism
  • Leukemia, Lymphocytic, Chronic, B-Cell / metabolism
  • Leukemia, Lymphocytic, Chronic, B-Cell / pathology
  • Male
  • Middle Aged
  • Toll-Like Receptor 7 / agonists
  • Toll-Like Receptor 7 / metabolism*
  • Tumor Cells, Cultured

Substances

  • Aminoquinolines
  • Antigens, CD19
  • Antineoplastic Agents
  • CD5 Antigens
  • Cytokines
  • Interleukin-6
  • Interleukin-8
  • TLR7 protein, human
  • Toll-Like Receptor 7
  • Imiquimod