Agomelatine improves sleep in a patient with fatal familial insomnia

Pharmacopsychiatry. 2012 Jan;45(1):34-6. doi: 10.1055/s-0031-1287778. Epub 2011 Oct 6.

Abstract

A young patient with FFI was started on agomelatine 25 mg to medicate nocturnal insomnia. Under this treatment sleep efficiency was improved, slow wave sleep was high and awakenings during sleep period time were far less than before. Clinically the patient was less restless during nighttime.

Publication types

  • Case Reports
  • Letter

MeSH terms

  • Acetamides / therapeutic use*
  • Adult
  • Epilepsy / etiology
  • Fatal Outcome
  • Female
  • Humans
  • Hypnotics and Sedatives / therapeutic use*
  • Insomnia, Fatal Familial / drug therapy*
  • Insomnia, Fatal Familial / physiopathology
  • Severity of Illness Index
  • Sleep Stages / drug effects
  • Treatment Outcome

Substances

  • Acetamides
  • Hypnotics and Sedatives
  • agomelatine