A simple "molecular beacon"-based fluorescent sensing strategy for sensitive and selective detection of mercury (II)

Chem Commun (Camb). 2011 Nov 28;47(44):12158-60. doi: 10.1039/c1cc14265h. Epub 2011 Oct 10.

Abstract

A novel fluorescent sensor for the detection of Hg(2+) in aqueous media was developed. The method takes advantages of the highly selective thymine-Hg(2+)-thymine coordination and the sensitive "signal-on" structure-switching molecular beacon.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • DNA, Single-Stranded / chemistry
  • Environmental Monitoring
  • Fluoresceins / chemistry
  • Fluorescence
  • Fluorescent Dyes / chemistry
  • Mercury / analysis*
  • Mercury / chemistry
  • Oligonucleotides / chemistry
  • Thymine / chemistry*
  • Water Pollutants, Chemical / analysis*
  • Water Pollutants, Chemical / chemistry
  • p-Dimethylaminoazobenzene / analogs & derivatives
  • p-Dimethylaminoazobenzene / chemistry

Substances

  • DNA, Single-Stranded
  • Fluoresceins
  • Fluorescent Dyes
  • Oligonucleotides
  • Water Pollutants, Chemical
  • 6-carboxyfluorescein
  • 4-(4-dimethylaminophenylazo)benzoic acid
  • p-Dimethylaminoazobenzene
  • Mercury
  • Thymine