Antibody recognition of fluorinated MUC1 glycopeptide antigens

Chem Commun (Camb). 2012 Feb 1;48(10):1487-9. doi: 10.1039/c1cc15139h. Epub 2011 Oct 10.

Abstract

The syntheses of various fluorinated MUC1 glycopeptide antigens and their specific binding to serum antibodies from mice immunized with natural and fluorinated TF(6)-MUC1-TTox conjugate vaccines are presented.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Animals
  • Antibodies / blood
  • Antibodies / chemistry*
  • Antibodies / immunology
  • Antigen-Antibody Reactions
  • Antigens / chemistry*
  • Antigens / immunology
  • Glycopeptides / chemical synthesis
  • Glycopeptides / chemistry*
  • Glycopeptides / immunology
  • Mice
  • Mucin-1 / chemistry*
  • Mucin-1 / immunology

Substances

  • Antibodies
  • Antigens
  • Glycopeptides
  • Mucin-1