Abstract
The biological fluorescent distribution of a model antitumor monofunctional platinum(II) complex bearing a 7-nitro-2,1,3-benzoxadiazole fluorophore can be visualized in breast carcinoma MCF-7 cells, pulmonary carcinoma A549 cells, kidney epithelial 293T cells, and zebrafish larva.
Publication types
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Research Support, Non-U.S. Gov't
MeSH terms
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Animals
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Antineoplastic Agents / chemistry*
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Antineoplastic Agents / metabolism*
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Cell Line, Tumor
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Chelating Agents / chemistry*
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Humans
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Larva / metabolism
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Light*
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Molecular Imaging / methods*
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Organoplatinum Compounds / chemistry*
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Organoplatinum Compounds / metabolism*
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Oxadiazoles / chemistry
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Spectrometry, Fluorescence
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Zebrafish
Substances
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7-nitrobenzoxadiazole
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Antineoplastic Agents
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Chelating Agents
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Organoplatinum Compounds
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Oxadiazoles