Indigo biosynthesis by Comamonas sp. MQ

Biotechnol Lett. 2012 Feb;34(2):353-7. doi: 10.1007/s10529-011-0778-2. Epub 2011 Oct 22.

Abstract

An indigo-producing strain was isolated from activated sludge and identified as Comamonas sp. based on 16S rRNA analysis. It produced indigo at 26.5 mg/l with a conversion of indole to indigo of 47%. Indole at 50 mg/l plus 200 mg naphthalene/l gave 32.2 mg indigo/l with a 58% conversion. A pathway for indigo formation is proposed. This is the first study of indigo biosynthesis by Comamonas sp.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Biosynthetic Pathways / genetics
  • Cluster Analysis
  • Comamonas / classification
  • Comamonas / genetics
  • Comamonas / isolation & purification
  • Comamonas / metabolism*
  • DNA, Bacterial / chemistry
  • DNA, Bacterial / genetics
  • DNA, Ribosomal / chemistry
  • DNA, Ribosomal / genetics
  • Indigo Carmine
  • Indoles / metabolism*
  • Molecular Sequence Data
  • Phylogeny
  • RNA, Ribosomal, 16S / genetics
  • Sequence Analysis, DNA
  • Sewage / microbiology*

Substances

  • DNA, Bacterial
  • DNA, Ribosomal
  • Indoles
  • RNA, Ribosomal, 16S
  • Sewage
  • Indigo Carmine

Associated data

  • GENBANK/HQ176414