Sleep-wake patterns of school-age children and adolescents before diagnosis and during induction chemotherapy for acute lymphocytic leukemia

J Pediatr Nurs. 2011 Dec;26(6):e37-44. doi: 10.1016/j.pedn.2011.02.006. Epub 2011 Jun 8.

Abstract

Sleep disturbances are commonly reported by children receiving chemotherapy for leukemia. Sleep patterns before diagnosis and during induction chemotherapy were evaluated in 38 children (7 to 18 years old). Child Sleep Assessment (CSA) was used to evaluate sleep patterns prior to diagnosis. Sleep diaries and actigraphy were used during chemotherapy. Adolescents went to bed later and awakened later than school-age children before diagnosis and during chemotherapy. During chemotherapy, children averaged 60 minutes of nighttime wake time. The early recognition of sleep problems associated with disease, treatment, and age is important for school-age children and adolescents with leukemia.

Publication types

  • Comparative Study
  • Research Support, N.I.H., Extramural

MeSH terms

  • Adolescent
  • Adolescent Behavior / drug effects
  • Child
  • Child Behavior / drug effects
  • Fatigue / epidemiology*
  • Fatigue / etiology
  • Female
  • Follow-Up Studies
  • Humans
  • Incidence
  • Induction Chemotherapy*
  • Longitudinal Studies
  • Male
  • Precursor Cell Lymphoblastic Leukemia-Lymphoma / diagnosis
  • Precursor Cell Lymphoblastic Leukemia-Lymphoma / drug therapy*
  • Precursor Cell Lymphoblastic Leukemia-Lymphoma / psychology
  • Prospective Studies
  • Risk Assessment
  • Sleep Stages / drug effects
  • Sleep Wake Disorders / epidemiology
  • Sleep Wake Disorders / etiology*
  • Sleep Wake Disorders / physiopathology
  • Time Factors