[Fetal and neonatal complications related to prolonged pregnancy]

J Gynecol Obstet Biol Reprod (Paris). 2011 Dec;40(8):717-25. doi: 10.1016/j.jgyn.2011.09.007. Epub 2011 Nov 5.
[Article in French]

Abstract

Objective: To evaluate fetal and neonatal outcomes related to prolonged pregnancy.

Methods: This study is based on Pubmed search, Cochrane library and HAS recommendations.

Results: The risk of fetal complications including macrosomia (6 %), oligohydramnios (10 %-15 %), abnormal fetal heart rate pattern and meconium-stained fluid is increased in prolonged pregnancy (≥ 41(+0) weeks). The rate of stillbirth was estimated between 1.6 ‰ and 3.0 ‰ live births according to countries in post-term pregnancies (≥ 42(+0) weeks). The risk of umbilical cord pH less than 7.10, Apgar score at five minutes inferior to 7, ICU admissions and perinatal asphyxia is increased in post-term infants (≥ 42(+0) weeks) compared with term infants. The risk of neurologic complications including neonatal convulsion, hypoxic ischemic encephalopathy, cerebral palsy, developmental deviations and epilepsy in childhood is increased in post-term infants. The risk of meconium aspiration syndrome, neonatal sepsis, and birth trauma including shoulder dystocia and bone fracture is increased in post-term infants. The rate of perinatal mortality increases in post-term infants. The perinatal mortality in post-term infants could be explained by perinatal asphyxia and meconium aspiration syndrome.

Conclusions: The risk of perinatal complications and mortality are increased in prolonged pregnancy.

Publication types

  • English Abstract
  • Review

MeSH terms

  • Female
  • Fetal Diseases / epidemiology*
  • Fetal Diseases / etiology
  • Fetal Diseases / mortality
  • France / epidemiology
  • Geography
  • Humans
  • Infant, Newborn
  • Infant, Newborn, Diseases / epidemiology*
  • Infant, Newborn, Diseases / etiology
  • Infant, Newborn, Diseases / mortality
  • Morbidity
  • Obstetric Labor Complications / epidemiology*
  • Obstetric Labor Complications / etiology
  • Obstetric Labor Complications / mortality
  • Pregnancy
  • Pregnancy Complications / epidemiology*
  • Pregnancy Complications / etiology
  • Pregnancy Complications / mortality
  • Pregnancy, Prolonged / epidemiology*
  • Pregnancy, Prolonged / etiology
  • Pregnancy, Prolonged / mortality