BEAMing sheds light on drug resistance

Clin Cancer Res. 2011 Dec 15;17(24):7508-10. doi: 10.1158/1078-0432.CCR-11-2556. Epub 2011 Nov 7.

Abstract

Targeted therapies against somatically altered genes are currently used for the treatment of many human cancers. The nascent technology known as BEAMing has the potential to increase the clinical utility of these agents because it allows for the detection of cancer mutations in peripheral blood, providing a rapid assessment of tumor mutation status.

Publication types

  • Comment

MeSH terms

  • Adenocarcinoma / genetics*
  • DNA Mutational Analysis / methods*
  • DNA, Neoplasm / genetics*
  • ErbB Receptors / genetics*
  • Female
  • Humans
  • Lung Neoplasms / genetics*
  • Male
  • Mutation*

Substances

  • DNA, Neoplasm
  • ErbB Receptors