Abstract
A biomimetic substrate for cell-culture is fabricated by plasma treatment of a prestressed thermoplastic shrink film to create tunable multiscaled alignment "wrinkles". Using this substrate, the functional alignment of human embryonic stem cell derived cardiomyocytes is demonstrated.
Copyright © 2011 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.
Publication types
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Research Support, N.I.H., Extramural
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Research Support, Non-U.S. Gov't
MeSH terms
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Action Potentials
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Animals
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Biomimetics
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Cell Differentiation
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Cells, Cultured
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Embryonic Stem Cells / cytology*
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Equipment Design
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Flow Cytometry / methods
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Humans
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Materials Testing
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Mice
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Myocardium / cytology*
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Myocytes, Cardiac / cytology*
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Rats
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Stem Cells / cytology
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Surface Properties