Abstract
Our results suggest the possible benefit of manipulating an intrinsic aging pathway that is independent of nutrition availability, a potential therapeutic route that might be able to bypass shortcomings of calorie restriction.
MeSH terms
-
Acetylation
-
Aging / physiology*
-
Animals
-
DNA Damage
-
Histone Acetyltransferases / metabolism
-
Humans
-
Protein Processing, Post-Translational*
-
Proteins / chemistry
-
Proteins / metabolism*
-
Saccharomyces cerevisiae / cytology
-
Saccharomyces cerevisiae / metabolism
-
Saccharomyces cerevisiae Proteins / metabolism
Substances
-
Proteins
-
Saccharomyces cerevisiae Proteins
-
Histone Acetyltransferases
-
NuA4 protein, S cerevisiae