Interaction of transketolase from human tissues with substrates

Biochemistry (Mosc). 2011 Sep;76(9):1061-4. doi: 10.1134/S0006297911090112.

Abstract

The Michaelis constant values for substrates of transketolase from human tissues were determined over a wide range of substrate concentrations. It is shown that K(m) values determined by other authors are significantly overestimated and explained why this is so.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Humans
  • Kinetics
  • Pentosephosphates / metabolism
  • Ribosemonophosphates / metabolism
  • Substrate Specificity
  • Transketolase / chemistry*
  • Transketolase / genetics
  • Transketolase / metabolism*

Substances

  • Pentosephosphates
  • Ribosemonophosphates
  • ribose-5-phosphate
  • xylulose-5-phosphate
  • Transketolase