Abstract
A 41-year-old man with metastases of a gastrointestinal stroma tumour was treated with an angiogenesis inhibitor. He presented with a distinct painful erythematous hyperkeratotic bullous hand-foot skin reaction. This was thought to be caused by the oral angiogenesis inhibitor and resolved after discontinuation of the therapy. This is a known adverse effect of angiogenesis inhibitors and is dose dependent.
Publication types
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Case Reports
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English Abstract
MeSH terms
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Adult
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Angiogenesis Inhibitors / adverse effects*
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Dose-Response Relationship, Drug
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Drug Eruptions / etiology*
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Drug Eruptions / pathology
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Foot Dermatoses / chemically induced*
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Foot Dermatoses / pathology
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Hand Dermatoses / chemically induced*
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Hand Dermatoses / pathology
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Humans
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Male
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Skin Diseases, Vesiculobullous / chemically induced*
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Skin Diseases, Vesiculobullous / pathology