(V600E)Braf::Tyr-CreERT2::K14-Kitl mice do not develop superficial spreading-like melanoma: keratinocyte Kit ligand is insufficient to "translocate" (V600E)Braf-driven melanoma to the epidermis

J Invest Dermatol. 2012 Feb;132(2):488-91. doi: 10.1038/jid.2011.341. Epub 2011 Nov 24.
No abstract available

Publication types

  • Letter
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Animals
  • Disease Models, Animal
  • Keratinocytes / metabolism*
  • Melanoma, Experimental / etiology*
  • Melanoma, Experimental / genetics
  • Mice
  • Mutation
  • Proto-Oncogene Proteins B-raf / genetics*
  • Skin Neoplasms / etiology*
  • Skin Neoplasms / genetics
  • Stem Cell Factor / physiology*

Substances

  • Stem Cell Factor
  • Braf protein, mouse
  • Proto-Oncogene Proteins B-raf