Potentiation of D-serine involves degeneration of dopaminergic neurons in MPTP/p mouse model of Parkinson's disease

CNS Neurosci Ther. 2011 Dec;17(6):796-8. doi: 10.1111/j.1755-5949.2011.00275.x.
No abstract available

Publication types

  • Letter
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Animals
  • Astrocytes / physiology
  • DNA-Binding Proteins
  • Dopamine / physiology*
  • Drug Synergism
  • Fluorescent Antibody Technique
  • Glial Fibrillary Acidic Protein / metabolism
  • MPTP Poisoning / pathology*
  • Male
  • Mesencephalon / cytology
  • Mesencephalon / metabolism
  • Mice
  • Mice, Inbred C57BL
  • Nerve Tissue Proteins / metabolism
  • Neurons / physiology*
  • Neurotransmitter Agents / physiology
  • Nuclear Proteins / metabolism
  • Parkinson Disease, Secondary / chemically induced
  • Parkinson Disease, Secondary / pathology*
  • Racemases and Epimerases / metabolism
  • Serine / physiology*
  • Tyrosine 3-Monooxygenase / metabolism

Substances

  • DNA-Binding Proteins
  • Glial Fibrillary Acidic Protein
  • Nerve Tissue Proteins
  • NeuN protein, mouse
  • Neurotransmitter Agents
  • Nuclear Proteins
  • Serine
  • Tyrosine 3-Monooxygenase
  • Racemases and Epimerases
  • serine racemase
  • Dopamine