An adult case of acute lymphoblastic leukemia with necrotizing leukoencephalopathy

T Tsukada; N Morita; T Ikeda; N Katayama; M Nishikawa; T Kobayashi; K Deguchi; S Shirakawa

doi:10.2169/internalmedicine1962.29.56

An adult case of acute lymphoblastic leukemia with necrotizing leukoencephalopathy

Jpn J Med. 1990 Jan-Feb;29(1):56-60. doi: 10.2169/internalmedicine1962.29.56.

Authors

T Tsukada¹, N Morita, T Ikeda, N Katayama, M Nishikawa, T Kobayashi, K Deguchi, S Shirakawa

Affiliation

¹ Second Department of Internal Medicine, Mie University School of Medicine, Tsu, Japan.

PMID: 2214347
DOI: 10.2169/internalmedicine1962.29.56

Abstract

A 19-year-old man with common acute lymphoblastic leukemia (ALL) developed necrotizing leukoencephalopathy (NL) after extensive chemotherapy and irradiation. Clinicians should exercise care in the treatment of leukemia, since chemotherapy has shown a trend of becoming more intensive, and the survival time of patients with leukemia is being extended.

Publication types

Case Reports

MeSH terms

Adult
Humans
Leukoencephalopathy, Progressive Multifocal / chemically induced*
Leukoencephalopathy, Progressive Multifocal / diagnostic imaging
Male
Methotrexate / adverse effects*
Necrosis
Precursor Cell Lymphoblastic Leukemia-Lymphoma / complications*
Precursor Cell Lymphoblastic Leukemia-Lymphoma / diagnostic imaging
Precursor Cell Lymphoblastic Leukemia-Lymphoma / drug therapy
Radionuclide Imaging
Tomography, X-Ray Computed

Substances

Methotrexate